PCL results for AraCyc pathway: de novo biosynthesis of purine nucleotides II

KEY: Each row represents a single gene that was identified by PLC (pathway-level co-expression) as being co-expressed with two or more genes in this pathway. Column 2 lists probe sets/genes that are co-expressed with annotated pathway members in column 3. Here, co-expression is defined as a regression p value less than 1e-80. If a gene in the first column is shaded blue, then it is already known to be a member of the pathway.

rank

probe set:gene id

co-expressed with

261301_at : AT1G48570
GO:0006355:regulation of transcription, DNA-dependent
GO:0004867:serine-type endopeptidase inhibitor activity
GO:0003677:DNA binding
GO:0005488:binding
GO:0009507:chloroplast

probe set,gene	slope	pvalue	rsquared	annotations
251599_at AT3G57610	0.475	2e-100	0.608	step: adenylosuccinate synthase GO:0004019:adenylosuccinate synthase activity GO:0006164:purine nucleotide biosynthesis GO:0005525:GTP binding GO:0009152:purine ribonucleotide biosynthesis GO:0009507:chloroplast
250403_at AT5G10920	0.692	3.01e-131	0.707	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	0.697	3.06e-90	0.568	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
253252_at AT4G34740	0.726	9.89e-85	0.545	step: amidophosphoribosyltransferase GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0004044:amidophosphoribosyltransferase activity GO:0004360:glutamine-fructose-6-phosphate transaminase (isomerizing) activity GO:0045982:negative regulation of purine base metabolism GO:0016740:transferase activity GO:0006529:asparagine biosynthesis GO:0004749:ribose phosphate diphosphokinase activity GO:0016564:transcriptional repressor activity GO:0009165:nucleotide biosynthesis GO:0009116:nucleoside metabolism GO:0008152:metabolism GO:0003677:DNA binding GO:0016051:carbohydrate biosynthesis GO:0016481:negative regulation of transcription GO:0004066:asparagine synthase (glutamine-hydrolyzing) activity GO:0009507:chloroplast
267421_at AT2G35040	0.715	2.67e-116	0.663	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
256978_at AT3G21110	0.589	3.64e-101	0.611	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
260294_at AT1G63660	0.572	7.7e-89	0.562	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
258243_at AT3G27740	0.464	1.24e-101	0.612	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast

256862_at : AT3G23940
GO:0004160:dihydroxy-acid dehydratase activity
GO:0009255:Entner-Doudoroff pathway
GO:0009099:valine biosynthesis
GO:0003824:catalytic activity
GO:0008152:metabolism
GO:0004456:phosphogluconate dehydratase activity
GO:0009097:isoleucine biosynthesis
GO:0009507:chloroplast
GO:0009082:branched chain family amino acid biosynthesis

probe set,gene	slope	pvalue	rsquared	annotations
251599_at AT3G57610	0.505	1.66e-132	0.711	step: adenylosuccinate synthase GO:0004019:adenylosuccinate synthase activity GO:0006164:purine nucleotide biosynthesis GO:0005525:GTP binding GO:0009152:purine ribonucleotide biosynthesis GO:0009507:chloroplast
250403_at AT5G10920	0.717	1.09e-164	0.787	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	0.769	1e-133	0.714	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	0.755	4.34e-154	0.765	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
256978_at AT3G21110	0.553	3.05e-87	0.555	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
258243_at AT3G27740	0.491	2.3e-132	0.71	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast
260294_at AT1G63660	0.551	6.61e-84	0.541	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
262754_at AT1G16350	0.811	1.38e-121	0.679	step: IMP dehydrogenase GO:0006177:GMP biosynthesis GO:0003938:IMP dehydrogenase activity GO:0003920:GMP reductase activity GO:0006568:tryptophan metabolism GO:0003824:catalytic activity GO:0009117:nucleotide metabolism GO:0006118:electron transport GO:0008152:metabolism GO:0000105:histidine biosynthesis GO:0004834:tryptophan synthase activity GO:0008372:cellular component unknown GO:0016491:oxidoreductase activity

260595_at : AT1G55890
GO:0000004:biological process unknown
GO:0005554:molecular function unknown
GO:0005739:mitochondrion

probe set,gene	slope	pvalue	rsquared	annotations
250403_at AT5G10920	0.845	1.32e-97	0.597	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	1.01	3.18e-119	0.672	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	0.92	4.7e-104	0.621	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
260294_at AT1G63660	0.797	1.24e-103	0.62	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
258243_at AT3G27740	0.639	6.21e-115	0.658	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast
256978_at AT3G21110	0.777	1.77e-98	0.6	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
262754_at AT1G16350	1.06	5.14e-107	0.632	step: IMP dehydrogenase GO:0006177:GMP biosynthesis GO:0003938:IMP dehydrogenase activity GO:0003920:GMP reductase activity GO:0006568:tryptophan metabolism GO:0003824:catalytic activity GO:0009117:nucleotide metabolism GO:0006118:electron transport GO:0008152:metabolism GO:0000105:histidine biosynthesis GO:0004834:tryptophan synthase activity GO:0008372:cellular component unknown GO:0016491:oxidoreductase activity

249315_at : AT5G41190
GO:0016151:nickel ion binding
GO:0005840:ribosome
GO:0006464:protein modification
GO:0005622:intracellular
GO:0003735:structural constituent of ribosome
GO:0006412:protein biosynthesis

probe set,gene	slope	pvalue	rsquared	annotations
250403_at AT5G10920	0.91	6.15e-106	0.628	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	1.02	1.84e-104	0.623	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	0.944	2.81e-96	0.592	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
260294_at AT1G63660	0.891	6.88e-129	0.701	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
253213_at AT4G34910	0.742	1.33e-110	0.644	step: adenylosuccinate synthase GO:0004019:adenylosuccinate synthase activity GO:0016151:nickel ion binding GO:0008026:ATP-dependent helicase activity GO:0006461:protein complex assembly GO:0004386:helicase activity GO:0008372:cellular component unknown GO:0003676:nucleic acid binding GO:0006164:purine nucleotide biosynthesis GO:0006259:DNA metabolism GO:0005524:ATP binding GO:0005525:GTP binding
256978_at AT3G21110	0.846	5.54e-111	0.645	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
258243_at AT3G27740	0.666	8.92e-112	0.648	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast

258715_at : AT3G09630
GO:0003735:structural constituent of ribosome
GO:0006412:protein biosynthesis
GO:0005840:ribosome
GO:0005622:intracellular

probe set,gene	slope	pvalue	rsquared	annotations
250403_at AT5G10920	1.06	1.15e-104	0.623	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	1.27	7.49e-130	0.703	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	1.11	3.97e-97	0.595	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
260294_at AT1G63660	0.946	2.17e-92	0.577	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
258243_at AT3G27740	0.806	1.99e-126	0.694	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast
256978_at AT3G21110	0.926	3.27e-89	0.564	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
262754_at AT1G16350	1.3	2.78e-106	0.629	step: IMP dehydrogenase GO:0006177:GMP biosynthesis GO:0003938:IMP dehydrogenase activity GO:0003920:GMP reductase activity GO:0006568:tryptophan metabolism GO:0003824:catalytic activity GO:0009117:nucleotide metabolism GO:0006118:electron transport GO:0008152:metabolism GO:0000105:histidine biosynthesis GO:0004834:tryptophan synthase activity GO:0008372:cellular component unknown GO:0016491:oxidoreductase activity

262880_at : AT1G64880
GO:0015935:small ribosomal subunit
GO:0016020:membrane
GO:0005622:intracellular
GO:0003735:structural constituent of ribosome
GO:0006412:protein biosynthesis
GO:0005840:ribosome

probe set,gene	slope	pvalue	rsquared	annotations
250403_at AT5G10920	0.683	2.27e-125	0.691	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	0.819	2.94e-162	0.782	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	0.659	8.07e-89	0.562	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
260294_at AT1G63660	0.606	6.04e-107	0.631	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
258243_at AT3G27740	0.464	9.42e-102	0.613	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast
256978_at AT3G21110	0.583	1.09e-97	0.597	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
262754_at AT1G16350	0.748	4.39e-88	0.559	step: IMP dehydrogenase GO:0006177:GMP biosynthesis GO:0003938:IMP dehydrogenase activity GO:0003920:GMP reductase activity GO:0006568:tryptophan metabolism GO:0003824:catalytic activity GO:0009117:nucleotide metabolism GO:0006118:electron transport GO:0008152:metabolism GO:0000105:histidine biosynthesis GO:0004834:tryptophan synthase activity GO:0008372:cellular component unknown GO:0016491:oxidoreductase activity

259311_at : AT3G05060
GO:0000004:biological process unknown
GO:0008372:cellular component unknown
GO:0003677:DNA binding

probe set,gene	slope	pvalue	rsquared	annotations
250403_at AT5G10920	0.581	4.11e-90	0.567	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	0.779	6.96e-174	0.805	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	0.648	2.94e-103	0.618	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
260294_at AT1G63660	0.54	1.92e-90	0.569	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
258243_at AT3G27740	0.437	7.28e-103	0.617	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast
256978_at AT3G21110	0.538	1.61e-92	0.577	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
262754_at AT1G16350	0.7	2.6e-87	0.556	step: IMP dehydrogenase GO:0006177:GMP biosynthesis GO:0003938:IMP dehydrogenase activity GO:0003920:GMP reductase activity GO:0006568:tryptophan metabolism GO:0003824:catalytic activity GO:0009117:nucleotide metabolism GO:0006118:electron transport GO:0008152:metabolism GO:0000105:histidine biosynthesis GO:0004834:tryptophan synthase activity GO:0008372:cellular component unknown GO:0016491:oxidoreductase activity

266057_at : AT2G40660
GO:0005737:cytoplasm
GO:0004825:methionine-tRNA ligase activity
GO:0004826:phenylalanine-tRNA ligase activity
GO:0000049:tRNA binding
GO:0006432:phenylalanyl-tRNA aminoacylation
GO:0006418:tRNA aminoacylation for protein translation
GO:0006412:protein biosynthesis
GO:0005524:ATP binding

probe set,gene	slope	pvalue	rsquared	annotations
250403_at AT5G10920	0.988	3.36e-108	0.636	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	1.2	3.93e-144	0.741	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
262943_at AT1G79470	0.893	1.74e-87	0.556	step: GMP reductase GO:0042545:cell wall modification GO:0003824:catalytic activity GO:0005618:cell wall GO:0003938:IMP dehydrogenase activity GO:0030599:pectinesterase activity GO:0003920:GMP reductase activity GO:0009117:nucleotide metabolism GO:0000105:histidine biosynthesis GO:0006177:GMP biosynthesis GO:0006118:electron transport GO:0016491:oxidoreductase activity
260294_at AT1G63660	0.943	1.54e-119	0.673	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
250484_at AT5G10240	0.735	5.15e-87	0.554	step: amidophosphoribosyltransferase//asparagine synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0004044:amidophosphoribosyltransferase activity GO:0004360:glutamine-fructose-6-phosphate transaminase (isomerizing) activity GO:0006529:asparagine biosynthesis GO:0016051:carbohydrate biosynthesis GO:0009113:purine base biosynthesis GO:0008152:metabolism GO:0004066:asparagine synthase (glutamine-hydrolyzing) activity
256978_at AT3G21110	0.906	5.85e-108	0.635	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
258243_at AT3G27740	0.673	2.75e-90	0.568	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast

263372_at : AT2G20450
GO:0003735:structural constituent of ribosome
GO:0007046:ribosome biogenesis
GO:0006412:protein biosynthesis
GO:0005840:ribosome
GO:0005622:intracellular

probe set,gene	slope	pvalue	rsquared	annotations
250403_at AT5G10920	0.712	1.02e-100	0.609	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	0.879	7.02e-141	0.733	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	0.722	7.14e-86	0.55	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
260294_at AT1G63660	0.643	6.41e-93	0.579	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
258243_at AT3G27740	0.523	1.77e-107	0.633	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast
256978_at AT3G21110	0.632	4.87e-91	0.571	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
262754_at AT1G16350	0.826	7.74e-87	0.554	step: IMP dehydrogenase GO:0006177:GMP biosynthesis GO:0003938:IMP dehydrogenase activity GO:0003920:GMP reductase activity GO:0006568:tryptophan metabolism GO:0003824:catalytic activity GO:0009117:nucleotide metabolism GO:0006118:electron transport GO:0008152:metabolism GO:0000105:histidine biosynthesis GO:0004834:tryptophan synthase activity GO:0008372:cellular component unknown GO:0016491:oxidoreductase activity

253558_at : AT4G31120
GO:0005737:cytoplasm
GO:0000036:acyl carrier activity
GO:0008276:protein methyltransferase activity
GO:0006633:fatty acid biosynthesis
GO:0008168:methyltransferase activity

probe set,gene	slope	pvalue	rsquared	annotations
250403_at AT5G10920	0.826	1.11e-106	0.63	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	0.968	5.65e-123	0.683	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	0.852	2.13e-95	0.589	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast
260294_at AT1G63660	0.832	1.69e-145	0.744	step: GMP synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006177:GMP biosynthesis GO:0009435:NAD biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006164:purine nucleotide biosynthesis GO:0004049:anthranilate synthase activity GO:0009113:purine base biosynthesis GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0009117:nucleotide metabolism GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0000105:histidine biosynthesis GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity GO:0005524:ATP binding
258243_at AT3G27740	0.572	8.56e-94	0.582	step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing) GO:0005737:cytoplasm GO:0006207:'de novo' pyrimidine base biosynthesis GO:0003922:GMP synthase (glutamine-hydrolyzing) activity GO:0006526:arginine biosynthesis GO:0004049:anthranilate synthase activity GO:0003824:catalytic activity GO:0009058:biosynthesis GO:0006807:nitrogen compound metabolism GO:0004086:carbamoyl-phosphate synthase activity GO:0008152:metabolism GO:0016763:transferase activity, transferring pentosyl groups GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0006177:GMP biosynthesis GO:0000105:histidine biosynthesis GO:0005524:ATP binding GO:0009507:chloroplast
256978_at AT3G21110	0.758	6.07e-107	0.631	step: phosphoribosylaminoimidazolesuccinocarboxamide synthase GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity GO:0006164:purine nucleotide biosynthesis GO:0009507:chloroplast
262754_at AT1G16350	0.937	1.85e-85	0.548	step: IMP dehydrogenase GO:0006177:GMP biosynthesis GO:0003938:IMP dehydrogenase activity GO:0003920:GMP reductase activity GO:0006568:tryptophan metabolism GO:0003824:catalytic activity GO:0009117:nucleotide metabolism GO:0006118:electron transport GO:0008152:metabolism GO:0000105:histidine biosynthesis GO:0004834:tryptophan synthase activity GO:0008372:cellular component unknown GO:0016491:oxidoreductase activity

254004_at : AT4G26300
GO:0004825:methionine-tRNA ligase activity
GO:0004812:tRNA ligase activity
GO:0006431:methionyl-tRNA aminoacylation
GO:0004814:arginine-tRNA ligase activity
GO:0006420:arginyl-tRNA aminoacylation
GO:0008372:cellular component unknown
GO:0006418:tRNA aminoacylation for protein translation
GO:0005524:ATP binding

probe set,gene	slope	pvalue	rsquared	annotations
251599_at AT3G57610	0.935	2.77e-102	0.615	step: adenylosuccinate synthase GO:0004019:adenylosuccinate synthase activity GO:0006164:purine nucleotide biosynthesis GO:0005525:GTP binding GO:0009152:purine ribonucleotide biosynthesis GO:0009507:chloroplast
250403_at AT5G10920	1.35	1.66e-129	0.702	step: adenylosuccinate lyase GO:0004018:adenylosuccinate lyase activity GO:0009152:purine ribonucleotide biosynthesis GO:0004056:argininosuccinate lyase activity GO:0045239:tricarboxylic acid cycle enzyme complex GO:0008797:aspartate ammonia-lyase activity GO:0006526:arginine biosynthesis GO:0003824:catalytic activity GO:0006106:fumarate metabolism GO:0006531:aspartate metabolism GO:0004333:fumarate hydratase activity GO:0009507:chloroplast
251830_at AT3G55010	1.42	4.53e-102	0.614	step: catalytic GO:0005737:cytoplasm GO:0009113:purine base biosynthesis GO:0009228:thiamin biosynthesis GO:0009030:thiamin phosphate kinase activity GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity GO:0004860:protein kinase inhibitor activity GO:0003824:catalytic activity GO:0005576:extracellular region GO:0006189:'de novo' IMP biosynthesis GO:0009405:pathogenesis GO:0009507:chloroplast
267421_at AT2G35040	1.28	6.59e-88	0.558	step: IMP cyclohydrolase GO:0003937:IMP cyclohydrolase activity GO:0006164:purine nucleotide biosynthesis GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0009507:chloroplast