University of Alabama at Birmingham Section on Statistical Genetics School of Public Health Department of Biostatistics

PCL results for AraCyc pathway: de novo biosynthesis of purine nucleotides I

KEY: Each row represents a single gene that was identified by PLC (pathway-level co-expression) as being co-expressed with two or more genes in this pathway. Column 2 lists probe sets/genes that are co-expressed with annotated pathway members in column 3. Here, co-expression is defined as a regression p value less than 1e-80. If a gene in the first column is shaded blue, then it is already known to be a member of the pathway.

rank probe set:gene id co-expressed with
1 259311_at : AT3G05060
GO:0000004:biological process unknown
GO:0008372:cellular component unknown
GO:0003677:DNA binding
probe set,gene slope pvalue rsquared annotations
250403_at
AT5G10920
0.581 4.11e-90 0.567 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
0.779 6.96e-174 0.805 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
255089_at
AT4G09320
0.296 9.5e-90 0.566 step: nucleoside-diphosphate kinase
GO:0006228:UTP biosynthesis
GO:0019690:pyrimidine deoxyribonucleoside interconversion
GO:0009218:pyrimidine ribonucleotide metabolism
GO:0006241:CTP biosynthesis
GO:0004550:nucleoside diphosphate kinase activity
GO:0005524:ATP binding
GO:0009117:nucleotide metabolism
GO:0008372:cellular component unknown
GO:0006183:GTP biosynthesis
267421_at
AT2G35040
0.648 2.94e-103 0.618 step: IMP cyclohydrolase
GO:0003937:IMP cyclohydrolase activity
GO:0006164:purine nucleotide biosynthesis
GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0009507:chloroplast
263882_at
AT2G21790
0.994 2.94e-121 0.678 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
256978_at
AT3G21110
0.538 1.61e-92 0.577 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
262754_at
AT1G16350
0.7 2.6e-87 0.556 step: IMP dehydrogenase
GO:0006177:GMP biosynthesis
GO:0003938:IMP dehydrogenase activity
GO:0003920:GMP reductase activity
GO:0006568:tryptophan metabolism
GO:0003824:catalytic activity
GO:0009117:nucleotide metabolism
GO:0006118:electron transport
GO:0008152:metabolism
GO:0000105:histidine biosynthesis
GO:0004834:tryptophan synthase activity
GO:0008372:cellular component unknown
GO:0016491:oxidoreductase activity
260294_at
AT1G63660
0.54 1.92e-90 0.569 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
258243_at
AT3G27740
0.437 7.28e-103 0.617 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
2 263372_at : AT2G20450
GO:0003735:structural constituent of ribosome
GO:0007046:ribosome biogenesis
GO:0006412:protein biosynthesis
GO:0005840:ribosome
GO:0005622:intracellular
probe set,gene slope pvalue rsquared annotations
250403_at
AT5G10920
0.712 1.02e-100 0.609 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
0.879 7.02e-141 0.733 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
255089_at
AT4G09320
0.354 9.43e-94 0.582 step: nucleoside-diphosphate kinase
GO:0006228:UTP biosynthesis
GO:0019690:pyrimidine deoxyribonucleoside interconversion
GO:0009218:pyrimidine ribonucleotide metabolism
GO:0006241:CTP biosynthesis
GO:0004550:nucleoside diphosphate kinase activity
GO:0005524:ATP binding
GO:0009117:nucleotide metabolism
GO:0008372:cellular component unknown
GO:0006183:GTP biosynthesis
267421_at
AT2G35040
0.722 7.14e-86 0.55 step: IMP cyclohydrolase
GO:0003937:IMP cyclohydrolase activity
GO:0006164:purine nucleotide biosynthesis
GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0009507:chloroplast
263882_at
AT2G21790
1.1 2.84e-97 0.596 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
256978_at
AT3G21110
0.632 4.87e-91 0.571 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
262754_at
AT1G16350
0.826 7.74e-87 0.554 step: IMP dehydrogenase
GO:0006177:GMP biosynthesis
GO:0003938:IMP dehydrogenase activity
GO:0003920:GMP reductase activity
GO:0006568:tryptophan metabolism
GO:0003824:catalytic activity
GO:0009117:nucleotide metabolism
GO:0006118:electron transport
GO:0008152:metabolism
GO:0000105:histidine biosynthesis
GO:0004834:tryptophan synthase activity
GO:0008372:cellular component unknown
GO:0016491:oxidoreductase activity
260294_at
AT1G63660
0.643 6.41e-93 0.579 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
258243_at
AT3G27740
0.523 1.77e-107 0.633 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
3 261301_at : AT1G48570
GO:0006355:regulation of transcription, DNA-dependent
GO:0004867:serine-type endopeptidase inhibitor activity
GO:0003677:DNA binding
GO:0005488:binding
GO:0009507:chloroplast
probe set,gene slope pvalue rsquared annotations
251599_at
AT3G57610
0.475 2e-100 0.608 step: adenylosuccinate synthase
GO:0004019:adenylosuccinate synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0005525:GTP binding
GO:0009152:purine ribonucleotide biosynthesis
GO:0009507:chloroplast
250403_at
AT5G10920
0.692 3.01e-131 0.707 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
0.697 3.06e-90 0.568 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
253252_at
AT4G34740
0.726 9.89e-85 0.545 step: amidophosphoribosyltransferase
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0004044:amidophosphoribosyltransferase activity
GO:0004360:glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0045982:negative regulation of purine base metabolism
GO:0016740:transferase activity
GO:0006529:asparagine biosynthesis
GO:0004749:ribose phosphate diphosphokinase activity
GO:0016564:transcriptional repressor activity
GO:0009165:nucleotide biosynthesis
GO:0009116:nucleoside metabolism
GO:0008152:metabolism
GO:0003677:DNA binding
GO:0016051:carbohydrate biosynthesis
GO:0016481:negative regulation of transcription
GO:0004066:asparagine synthase (glutamine-hydrolyzing) activity
GO:0009507:chloroplast
267421_at
AT2G35040
0.715 2.67e-116 0.663 step: IMP cyclohydrolase
GO:0003937:IMP cyclohydrolase activity
GO:0006164:purine nucleotide biosynthesis
GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0009507:chloroplast
263882_at
AT2G21790
0.954 3.97e-86 0.551 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
256978_at
AT3G21110
0.589 3.64e-101 0.611 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
260294_at
AT1G63660
0.572 7.7e-89 0.562 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
258243_at
AT3G27740
0.464 1.24e-101 0.612 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
4 256862_at : AT3G23940
GO:0004160:dihydroxy-acid dehydratase activity
GO:0009255:Entner-Doudoroff pathway
GO:0009099:valine biosynthesis
GO:0003824:catalytic activity
GO:0008152:metabolism
GO:0004456:phosphogluconate dehydratase activity
GO:0009097:isoleucine biosynthesis
GO:0009507:chloroplast
GO:0009082:branched chain family amino acid biosynthesis
probe set,gene slope pvalue rsquared annotations
251599_at
AT3G57610
0.505 1.66e-132 0.711 step: adenylosuccinate synthase
GO:0004019:adenylosuccinate synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0005525:GTP binding
GO:0009152:purine ribonucleotide biosynthesis
GO:0009507:chloroplast
250403_at
AT5G10920
0.717 1.09e-164 0.787 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
0.769 1e-133 0.714 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
267421_at
AT2G35040
0.755 4.34e-154 0.765 step: IMP cyclohydrolase
GO:0003937:IMP cyclohydrolase activity
GO:0006164:purine nucleotide biosynthesis
GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0009507:chloroplast
263882_at
AT2G21790
1.08 3.52e-142 0.736 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
256978_at
AT3G21110
0.553 3.05e-87 0.555 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
262754_at
AT1G16350
0.811 1.38e-121 0.679 step: IMP dehydrogenase
GO:0006177:GMP biosynthesis
GO:0003938:IMP dehydrogenase activity
GO:0003920:GMP reductase activity
GO:0006568:tryptophan metabolism
GO:0003824:catalytic activity
GO:0009117:nucleotide metabolism
GO:0006118:electron transport
GO:0008152:metabolism
GO:0000105:histidine biosynthesis
GO:0004834:tryptophan synthase activity
GO:0008372:cellular component unknown
GO:0016491:oxidoreductase activity
260294_at
AT1G63660
0.551 6.61e-84 0.541 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
258243_at
AT3G27740
0.491 2.3e-132 0.71 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
5 259096_at : AT3G04840
GO:0003735:structural constituent of ribosome
GO:0006412:protein biosynthesis
GO:0005843:cytosolic small ribosomal subunit (sensu Eukaryota)
probe set,gene slope pvalue rsquared annotations
250403_at
AT5G10920
0.968 1.08e-117 0.667 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
1.13 1.81e-135 0.719 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
255089_at
AT4G09320
0.459 4.26e-93 0.579 step: nucleoside-diphosphate kinase
GO:0006228:UTP biosynthesis
GO:0019690:pyrimidine deoxyribonucleoside interconversion
GO:0009218:pyrimidine ribonucleotide metabolism
GO:0006241:CTP biosynthesis
GO:0004550:nucleoside diphosphate kinase activity
GO:0005524:ATP binding
GO:0009117:nucleotide metabolism
GO:0008372:cellular component unknown
GO:0006183:GTP biosynthesis
263882_at
AT2G21790
1.49 1.05e-112 0.651 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
256978_at
AT3G21110
0.814 2.01e-88 0.56 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
258243_at
AT3G27740
0.673 1.51e-104 0.623 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
250484_at
AT5G10240
0.695 4.26e-84 0.542 step: amidophosphoribosyltransferase//asparagine synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0004044:amidophosphoribosyltransferase activity
GO:0004360:glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0006529:asparagine biosynthesis
GO:0016051:carbohydrate biosynthesis
GO:0009113:purine base biosynthesis
GO:0008152:metabolism
GO:0004066:asparagine synthase (glutamine-hydrolyzing) activity
260294_at
AT1G63660
0.831 2.17e-91 0.573 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
262754_at
AT1G16350
1.06 1.14e-83 0.54 step: IMP dehydrogenase
GO:0006177:GMP biosynthesis
GO:0003938:IMP dehydrogenase activity
GO:0003920:GMP reductase activity
GO:0006568:tryptophan metabolism
GO:0003824:catalytic activity
GO:0009117:nucleotide metabolism
GO:0006118:electron transport
GO:0008152:metabolism
GO:0000105:histidine biosynthesis
GO:0004834:tryptophan synthase activity
GO:0008372:cellular component unknown
GO:0016491:oxidoreductase activity
6 247566_at : AT5G61170
GO:0003735:structural constituent of ribosome
GO:0006412:protein biosynthesis
GO:0005840:ribosome
GO:0005622:intracellular
probe set,gene slope pvalue rsquared annotations
248506_at
AT5G50370
0.656 1.46e-81 0.531 step: adenylate kinase
GO:0006139:nucleobase, nucleoside, nucleotide and nucleic acid metabolism
GO:0019201:nucleotide kinase activity
GO:0046034:ATP metabolism
GO:0016776:phosphotransferase activity, phosphate group as acceptor
GO:0004017:adenylate kinase activity
GO:0009061:anaerobic respiration
GO:0009117:nucleotide metabolism
GO:0005739:mitochondrion
GO:0005524:ATP binding
250403_at
AT5G10920
0.803 1.1e-110 0.644 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
0.918 4.08e-117 0.665 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
255089_at
AT4G09320
0.371 1.03e-81 0.531 step: nucleoside-diphosphate kinase
GO:0006228:UTP biosynthesis
GO:0019690:pyrimidine deoxyribonucleoside interconversion
GO:0009218:pyrimidine ribonucleotide metabolism
GO:0006241:CTP biosynthesis
GO:0004550:nucleoside diphosphate kinase activity
GO:0005524:ATP binding
GO:0009117:nucleotide metabolism
GO:0008372:cellular component unknown
GO:0006183:GTP biosynthesis
263882_at
AT2G21790
1.2 2.82e-95 0.588 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
256978_at
AT3G21110
0.671 2e-82 0.535 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
262754_at
AT1G16350
0.907 5.73e-87 0.554 step: IMP dehydrogenase
GO:0006177:GMP biosynthesis
GO:0003938:IMP dehydrogenase activity
GO:0003920:GMP reductase activity
GO:0006568:tryptophan metabolism
GO:0003824:catalytic activity
GO:0009117:nucleotide metabolism
GO:0006118:electron transport
GO:0008152:metabolism
GO:0000105:histidine biosynthesis
GO:0004834:tryptophan synthase activity
GO:0008372:cellular component unknown
GO:0016491:oxidoreductase activity
260294_at
AT1G63660
0.712 1.87e-95 0.589 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
258243_at
AT3G27740
0.535 1.81e-86 0.552 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
7 264806_at : AT1G08610
GO:0003735:structural constituent of ribosome
GO:0015934:large ribosomal subunit
GO:0006412:protein biosynthesis
probe set,gene slope pvalue rsquared annotations
258106_at
AT3G23580
0.606 9.26e-95 0.586 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0009186:deoxyribonucleoside diphosphate metabolism
GO:0009259:ribonucleotide metabolism
251830_at
AT3G55010
0.782 1.73e-106 0.63 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
267421_at
AT2G35040
0.779 7.62e-127 0.695 step: IMP cyclohydrolase
GO:0003937:IMP cyclohydrolase activity
GO:0006164:purine nucleotide biosynthesis
GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0009507:chloroplast
263882_at
AT2G21790
1.05 1.29e-94 0.586 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
256978_at
AT3G21110
0.629 5.1e-102 0.614 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
258243_at
AT3G27740
0.513 4.66e-116 0.662 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
260294_at
AT1G63660
0.626 3.37e-97 0.596 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
250403_at
AT5G10920
0.696 5.26e-107 0.632 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
8 249315_at : AT5G41190
GO:0016151:nickel ion binding
GO:0005840:ribosome
GO:0006464:protein modification
GO:0005622:intracellular
GO:0003735:structural constituent of ribosome
GO:0006412:protein biosynthesis
probe set,gene slope pvalue rsquared annotations
250403_at
AT5G10920
0.91 6.15e-106 0.628 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
1.02 1.84e-104 0.623 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
253213_at
AT4G34910
0.742 1.33e-110 0.644 step: adenylosuccinate synthase
GO:0004019:adenylosuccinate synthase activity
GO:0016151:nickel ion binding
GO:0008026:ATP-dependent helicase activity
GO:0006461:protein complex assembly
GO:0004386:helicase activity
GO:0008372:cellular component unknown
GO:0003676:nucleic acid binding
GO:0006164:purine nucleotide biosynthesis
GO:0006259:DNA metabolism
GO:0005524:ATP binding
GO:0005525:GTP binding
267421_at
AT2G35040
0.944 2.81e-96 0.592 step: IMP cyclohydrolase
GO:0003937:IMP cyclohydrolase activity
GO:0006164:purine nucleotide biosynthesis
GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0009507:chloroplast
263882_at
AT2G21790
1.37 5.02e-93 0.579 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
260294_at
AT1G63660
0.891 6.88e-129 0.701 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
256978_at
AT3G21110
0.846 5.54e-111 0.645 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
258243_at
AT3G27740
0.666 8.92e-112 0.648 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
9 258715_at : AT3G09630
GO:0003735:structural constituent of ribosome
GO:0006412:protein biosynthesis
GO:0005840:ribosome
GO:0005622:intracellular
probe set,gene slope pvalue rsquared annotations
250403_at
AT5G10920
1.06 1.15e-104 0.623 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
1.27 7.49e-130 0.703 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis
GO:0009405:pathogenesis
GO:0009507:chloroplast
267421_at
AT2G35040
1.11 3.97e-97 0.595 step: IMP cyclohydrolase
GO:0003937:IMP cyclohydrolase activity
GO:0006164:purine nucleotide biosynthesis
GO:0004643:phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0009507:chloroplast
263882_at
AT2G21790
1.64 5.02e-101 0.61 step: ribonucleoside-diphosphate reductase
GO:0005971:ribonucleoside-diphosphate reductase complex
GO:0004748:ribonucleoside-diphosphate reductase activity
GO:0006260:DNA replication
256978_at
AT3G21110
0.926 3.27e-89 0.564 step: phosphoribosylaminoimidazolesuccinocarboxamide synthase
GO:0004639:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0006164:purine nucleotide biosynthesis
GO:0009507:chloroplast
258243_at
AT3G27740
0.806 1.99e-126 0.694 step: GMP synthase (glutamine-hydrolyzing)//carbamoyl-phosphate synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006207:'de novo' pyrimidine base biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006526:arginine biosynthesis
GO:0004049:anthranilate synthase activity
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0006807:nitrogen compound metabolism
GO:0004086:carbamoyl-phosphate synthase activity
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0004088:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0006177:GMP biosynthesis
GO:0000105:histidine biosynthesis
GO:0005524:ATP binding
GO:0009507:chloroplast
260294_at
AT1G63660
0.946 2.17e-92 0.577 step: GMP synthase (glutamine-hydrolyzing)
GO:0005737:cytoplasm
GO:0006177:GMP biosynthesis
GO:0009435:NAD biosynthesis
GO:0003922:GMP synthase (glutamine-hydrolyzing) activity
GO:0006164:purine nucleotide biosynthesis
GO:0004049:anthranilate synthase activity
GO:0009113:purine base biosynthesis
GO:0003824:catalytic activity
GO:0009058:biosynthesis
GO:0009117:nucleotide metabolism
GO:0008152:metabolism
GO:0016763:transferase activity, transferring pentosyl groups
GO:0000105:histidine biosynthesis
GO:0003952:NAD+ synthase (glutamine-hydrolyzing) activity
GO:0005524:ATP binding
262754_at
AT1G16350
1.3 2.78e-106 0.629 step: IMP dehydrogenase
GO:0006177:GMP biosynthesis
GO:0003938:IMP dehydrogenase activity
GO:0003920:GMP reductase activity
GO:0006568:tryptophan metabolism
GO:0003824:catalytic activity
GO:0009117:nucleotide metabolism
GO:0006118:electron transport
GO:0008152:metabolism
GO:0000105:histidine biosynthesis
GO:0004834:tryptophan synthase activity
GO:0008372:cellular component unknown
GO:0016491:oxidoreductase activity
10 262880_at : AT1G64880
GO:0015935:small ribosomal subunit
GO:0016020:membrane
GO:0005622:intracellular
GO:0003735:structural constituent of ribosome
GO:0006412:protein biosynthesis
GO:0005840:ribosome
probe set,gene slope pvalue rsquared annotations
250403_at
AT5G10920
0.683 2.27e-125 0.691 step: adenylosuccinate lyase
GO:0004018:adenylosuccinate lyase activity
GO:0009152:purine ribonucleotide biosynthesis
GO:0004056:argininosuccinate lyase activity
GO:0045239:tricarboxylic acid cycle enzyme complex
GO:0008797:aspartate ammonia-lyase activity
GO:0006526:arginine biosynthesis
GO:0003824:catalytic activity
GO:0006106:fumarate metabolism
GO:0006531:aspartate metabolism
GO:0004333:fumarate hydratase activity
GO:0009507:chloroplast
251830_at
AT3G55010
0.819 2.94e-162 0.782 step: catalytic
GO:0005737:cytoplasm
GO:0009113:purine base biosynthesis
GO:0009228:thiamin biosynthesis
GO:0009030:thiamin phosphate kinase activity
GO:0004641:phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0004860:protein kinase inhibitor activity
GO:0003824:catalytic activity
GO:0005576:extracellular region
GO:0006189:'de novo' IMP biosynthesis